Coagulation Instrumentation Updates at Atrium, UVMC

Premier Pulse     March 2019

New Coagulation Normal ranges, Heparin Protocol for APTT, and Critical Values

Atrium Medical Center and Upper Valley Medical Center are going live with new coagulation instrumentation as of March 27. Miami Valley Hospital went live on January 30.

Through a large group effort, including collaboration with pharmacy, we have studied the normal ranges for PT, APTT, Fibrinogen, and D-dimer testing. The laboratory has also studied very closely the heparin protocol for APTT.

Based on these studies and the change in instrument method, new normal and critical ranges are required. New normal and critical value ranges are as follows:

PT (Partial Thromboplastin Time) = 11.7-13.9 seconds
APTT (Activated Partial Thromboplastin Time) = 24.5-35.2 seconds
FIBRINOGEN = 208-491 mg/dl
D-DIMER = <0.50 ug/ml FEU cut off. *Units different for Atrium Medical Center only.
HEPARIN PROTOCOL FOR APTT (therapeutic range) = 74.0-110.0 seconds

INR > 5.0 
APTT (Activated Partial Thromboplastin Time) >60.0 seconds
FIBRINOGEN < 75 mg/dl
HEPARIN PROTOCOL FOR APTT <74.0 or >110.0 seconds

For questions or concerns, please call Catherine Hoesl, MT (ASCP), at (513) 484-3558(513) 484-3558.

Back to the March 2019 issue of Premier Pulse