Premier Health providers answer frequently asked questions about stroke.

How does tPA work?

Dr. Bryan Ludwig explains tPA and how it works. Click play to watch the video or read the transcript


Tissue plasminogen activator (tPA) is used to treat ischemic strokes, strokes in which blood flow to the brain is blocked by a clot in a blood vessel, according to the American Stroke AssociationOff Site Icon. A patient’s chance of recovering from an ischemic stroke improve when tPA is administered within three hours of the event, according to the ASA.

According to the National Stroke AssociationOff Site Icon, tPA is the only drug treatment approved by the Food and Drug Administration.

For more information about tPA treatment, talk to your doctor.

Learn more:

Source: Bryan Ludwig, MD, Clinical Neuroscience Institute; John Terry, MD, Clinical Neuroscience Institute; Elizabeth Marriott, MD, Clinical Neuroscience Institute

Schedule an appointment

If you think you are having a stroke, dial 911 immediately. To schedule an appointment with a neurologist, call (866) 608-FIND(866) 608-FIND or complete the form below to receive a call from our scheduling department to make an appointment.